10. Michael C. Hall and Jennifer Carpenter
For those of you who thought it was a bit creepy that these two hooked up - what with them playing brother and (step) sister on Dexter and all - this one's for you. The pair began dating in 2007 while working on the hit Showtime series and eloped on New Year's Eve 2009. Jennifer stood by her man during his battle with Hodgkin's lymphoma (which he happily won) and, hours after Michael received a SAG Award nomination for his work on Dexter, Jennifer filed for divorce, citing...you guessed it...irreconcilable differences! Rumors, like blood splatter, are everywhere as to why what appeared to be such a strong union came to an end. Reports from Access Hollywood state that Jennifer was grousing about her relationship woes on the set of Dexter and of course, there's Julia Stiles, who played Dexter's romantic interest this past season. With a sixth season on the way, it will be interesting to what direction the show's storyline takes, depending on the way this divorce pans out.